By James R. O'Dell, Josef S. Smolen (auth.), John H. Stone (eds.)

A Clinician's Pearls and Myths in Rheumatology is a wealthy assemblage of the medical knowledge of specialist rheumatologists from an entire variety of specialties and nationalities. It examines the nuggets of knowledge, or ‘pearls’ won from collective scientific event concerning the analysis or remedy of assorted illnesses when additionally aiming to debunk definite myths that experience motivated the perform of many clinicians yet have confirmed false.

The pithy form of writing guarantees that the reader completely enjoys delving into this trove of diagnostic and healing counsel. furthermore, an abundance of illustrations, together with three hundred medical images, considerably augments the reader’s realizing of those ‘pearls’.

With contributions from 126 authors around the numerous subspecialties in rheumatology, and comprising a complete of greater than 1400 Pearls and Myths, this publication actually presents the corpus of present medical knowledge in rheumatology.

Dr John H. Stone, MD MPH is scientific Director of Rheumatology at Massachusetts common health facility, Boston, MA. He has pioneered loads of medical learn in rheumatology, quite within the sector of systemic vasculitis.

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Extra info for A Clinician's Pearls and Myths in Rheumatology

Sample text

In: Hochberg MC, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH (eds) Rheumatology (4th edn). Philadelphia, PA, Mosby, 2008, pp. 773–783 Turesson C, O’Fallon WM, Crowson C, et al Extraarticular disease manifestations in rheumatoid arthritis: Incidence, trends, and risk factors over 46 years. Annals of Rheumatic Disease 2003; 62:722–727 Turesson, C, McClelland, R, Christianson, TJ, Matteson, EL. No decrease over time in the incidence of vasculitis or other extra-artic-ular manifestations in rheumatoid arthritis (abstract).

However, anakinra is a difficult drug to use, not only because of the requirement for daily parenteral injections but also the frequent and sometimes dramatic skin rashes associated with this agent. Such reactions tend to resolve within a few weeks of continued administration, but newer IL-1 blocking agents with greater ease of administration are welcome. Myth: The presence of hepatic, pulmonary, and cardiac involvement decreases the likelihood of AOSD and adds new urgency to the search for vasculitis or an infectious etiology of the patient’s problems.

2005; Bresnihan 2008). Some patients with treatment-resistant AOSD have experienced striking responses to IL-1 inhibition. This author has even used responsiveness to anakinra as a diagnostic test for AOSD in some patients. However, anakinra is a difficult drug to use, not only because of the requirement for daily parenteral injections but also the frequent and sometimes dramatic skin rashes associated with this agent. Such reactions tend to resolve within a few weeks of continued administration, but newer IL-1 blocking agents with greater ease of administration are welcome.

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